Cosmelan®MD temporarily reduces hyperpigmentation, and the length of the results can vary. Continued use of Cosmelan®MD cream after the initial treatment period, exposure to sun and UV light, hormone fluctuations, and other factors may all affect the longevity of your results. For continued suppression of melanin production and lightening of skin discoloration, treatment with Cosmelan®MD may need to occur every few months. We will help you determine how frequently you might need to repeat your Cosmelan®MD treatment during your initial consultation to ensure prolonged results.